Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10460812 | 0.93 | RAB9A (0.71) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL30982342 | 0.93 | RAB9A (0.71) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5170654 | 0.90 | MAPT (0.69) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18816619 | 0.90 | MAPT (0.69) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL28057988 | 0.85 | RAB9A (0.61) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6031547 | 0.84 | KDM4E (0.79) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29357142 | 0.84 | KDM4E (0.79) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18844291 | 0.83 | MAPT (0.69) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL2485504 | 0.82 | MAPT (0.66) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL334906 | 0.82 | MAPT (0.66) | RAB9ANPC1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342635-B1 | Azacyclic carboxylic acid derivatives, their preparation and use | NOVO NORDISK AS (DK) | 1994-08-17 | — | — | EP | disclosed |
| EP-0342635-A1 | Azacyclic carboxylic acid derivatives, their preparation and use | NOVO NORDISK A/S (DK) | 1989-11-23 | — | — | EP | disclosed |