Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137970 | 0.81 | TTR (0.47) | PRMT1EGFRPIM1MEN1KMT2A | |
| SCHEMBL30067921 | 0.81 | TTR (0.47) | PRMT1EGFRPIM1MEN1KMT2A | |
| SCHEMBL3417492 | 0.79 | EGFR (0.76) | EGFRPIM1MEN1KMT2AALDH1A1 | |
| SCHEMBL9397152 | 0.79 | CYP1B1 (0.50) | EGFRPIM1MEN1KMT2AALDH1A1 | |
| SCHEMBL5816933 | 0.78 | EGFR (0.64) | EGFRPIM1MEN1KMT2AALDH1A1 | |
| SCHEMBL8947495 | 0.77 | EGFR (0.73) | EGFRPIM1MEN1KMT2AALDH1A1 | |
| SCHEMBL11201120 | 0.77 | KMT2A (0.61) | PRMT1EGFRPIM1CASP3MEN1 | |
| SCHEMBL3819746 | 0.77 | MEN1 (0.51) | PRMT1CASP3MEN1KMT2AALDH1A1 | |
| SCHEMBL7792566 | 0.76 | EGFR (0.71) | EGFRPIM1MEN1KMT2AALDH1A1 | |
| SCHEMBL2186275 | 0.76 | PRMT1 (0.63) | PRMT1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027969-A1 | ISOQUINOLINETRIONE DERIVATIVES AS HERBICIDES | ZENECA LIMITED (GB) | 1994-12-08 | — | — | WO | disclosed |