Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12235607 | 0.90 | CYP1B1 (0.53) | CYP1B1EGFRPIM1ALDH1A1MEN1 | |
| SCHEMBL9397268 | 0.79 | PRMT1 (0.55) | EGFRPIM1ALDH1A1MEN1KMT2A | |
| SCHEMBL9397263 | 0.78 | CYP1B1 (0.60) | CYP1B1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9393324 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9437188 | 0.77 | PRMT1 (0.70) | CYP1B1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3417492 | 0.75 | EGFR (0.76) | EGFRPIM1ALDH1A1MEN1KMT2A | |
| SCHEMBL8947495 | 0.74 | EGFR (0.73) | EGFRPIM1ALDH1A1MEN1KMT2A | |
| SCHEMBL9397083 | 0.73 | S100A4 (0.54) | CYP1B1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14876148 | 0.73 | TDP1 (0.64) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL7792566 | 0.72 | EGFR (0.71) | EGFRPIM1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027969-A1 | ISOQUINOLINETRIONE DERIVATIVES AS HERBICIDES | ZENECA LIMITED (GB) | 1994-12-08 | — | — | WO | disclosed |