Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841171 | 0.89 | CYP1A2 (0.57) | KMT2AMAPK1KDM4EMEN1TP53 | |
| SCHEMBL29756433 | 0.89 | CYP1A2 (0.57) | KMT2AMAPK1KDM4EMEN1TP53 | |
| SCHEMBL4324560 | 0.89 | CYP1A2 (0.57) | KMT2AMAPK1KDM4EMEN1TP53 | |
| Hydrochloric Acid SCHEMBL10407517 | 0.87 | APOBEC3A (0.58) | KMT2AMAPK1KDM4EMEN1TP53 | |
| SCHEMBL16850419 | 0.85 | CRHBP (0.50) | KMT2AMEN1CYP1A2CHRM2SLC6A4 | |
| SCHEMBL20490913 | 0.84 | CXCR4 (0.47) | KMT2AMEN1CHRM2SMN1; SMN2 | |
| SCHEMBL9397289 | 0.83 | CXCR4 (0.60) | KMT2AMEN1CYP1A2CHRM2SLC6A4 | |
| Hydrochloric Acid SCHEMBL15302696 | 0.83 | KMT2A (0.51) | KMT2AMAPK1KDM4EMEN1TP53 | |
| SCHEMBL23943837 | 0.82 | CHRM2 (0.48) | KMT2AMAPK1KDM4EMEN1TP53 | |
| SCHEMBL18970191 | 0.80 | ALDH1A1 (0.56) | KMT2AMEN1CYP1A2CHRM2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021208963-A1 | BCL-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-10-21 | — | — | WO | disclosed |