Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061907 | 0.84 | OPRM1 (0.56) | CYP2D6OPRM1DRD4DRD3DRD2 | |
| SCHEMBL8059835 | 0.84 | OPRM1 (0.56) | CYP2D6OPRM1DRD4DRD3DRD2 | |
| SCHEMBL504205 | 0.84 | OPRM1 (0.56) | CYP2D6OPRM1DRD4DRD3DRD2 | |
| SCHEMBL9450076 | 0.79 | CYP2D6 (0.45) | CYP2D6OPRM1DRD4DRD3DRD2 | |
| SCHEMBL11619910 | 0.78 | CYP2D6 (0.70) | CYP2D6OPRM1DRD4DRD3DRD2 | |
| SCHEMBL9581143 | 0.78 | CYP3A4 (0.60) | CYP2D6OPRM1DRD4DRD3DRD2 | |
| SCHEMBL10838731 | 0.76 | CYP3A4 (0.59) | CYP2D6CYP3A4CHRM2CYP2C19OPRK1 | |
| SCHEMBL11471791 | 0.76 | CCR1 (0.46) | CYP2D6OPRM1DRD4DRD3DRD2 | |
| SCHEMBL11600408 | 0.75 | CYP3A4 (0.55) | CYP2D6OPRM1DRD4DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL11114957 | 0.75 | CYP3A4 (0.58) | CYP2D6CYP3A4CHRM2CYP2C19OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452809-B1 | A therapeutic agent for pollakiuria, urinary urgency or incontinence of urine comprising alpha-phenyl-alpha-pyridylalkanoic acid derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5202331-A | THERAPEUTIC AGENT FOR DYSURIA COMPRISING ALPHA-PHENYL-ALPHA-PYRIDYLALKANOIC ACID DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0452809-A2 | A therapeutic agent for pollakiuria, urinary urgency or incontinence of urine comprising alpha-phenyl-alpha-pyridylalkanoic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-23 | — | — | EP | disclosed |
| EP-0105458-B1 | ALPHA-ARYL-ALPHA-PYRIDYLALKANOIC ACID DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-11-23 | — | — | EP | disclosed |
| US-4564621-A | ANTIULCER AND ANTISPASMODIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-14 | — | — | US | disclosed |