SCHEMBL9397333

SCHEMBL9397333

O=C(CC1(NC(=O)OCc2ccccc2)CCCCC1)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.43
CTSL P07711 1/20 0.43
CTSB P07858 1/20 0.43
CTSS P25774 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
BCL9 O00512 1/20 0.40
CTNNB1 P35222 1/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
THRB P10828 1/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9398327 0.80 CTSS (0.53) CTSLCTSBCTSSALDH1A1MAPK1
SCHEMBL4110578 0.78 CTSS (0.55) CTSLCTSBCTSSALDH1A1SMN1; SMN2
SCHEMBL1803004 0.77 ATM (0.55) HTR2ANPC1RAB9ABCL9CTNNB1
SCHEMBL8944353 0.76 BCL9 (0.52) HTR2ANPC1RAB9ABCL9CTNNB1
SCHEMBL1714950 0.75 HTR2A (0.70) HTR2ANPC1RAB9ABCL9CTNNB1
SCHEMBL27875249 0.75 RAB9A (0.49) NPC1RAB9A
SCHEMBL8387745 0.75 CTSS (0.53) HTR2ACTSLCTSBCTSSRAB9A
SCHEMBL7311119 0.75 BCL9 (0.43) BCL9CTNNB1ALDH1A1CYP2C9CYP2C19
SCHEMBL7121567 0.74 CTSS (0.56) CTSLCTSBCTSSNPC1RAB9A
SCHEMBL11415434 0.74 HTT (0.58) BCL9CTNNB1CYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5371267-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1994-12-06 US disclosed