Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28334070 | 1.00 | CA2 (0.43) | CA2ALDH1A1ALOX15TSHRLAP3 | |
| Phosphoric Acid SCHEMBL28405846 | 1.00 | CA2 (0.43) | CA2ALDH1A1ALOX15TSHRLAP3 | |
| Phosphoric Acid SCHEMBL28992572 | 1.00 | CA2 (0.43) | CA2ALDH1A1ALOX15TSHRLAP3 | |
| Phosphoric Acid SCHEMBL1075962 | 1.00 | CA2 (0.43) | CA2ALDH1A1ALOX15TSHRLAP3 | |
| Phosphoric Acid SCHEMBL4553439 | 1.00 | CA2 (0.43) | CA2ALDH1A1ALOX15TSHRLAP3 | |
| Phosphoric Acid SCHEMBL29255680 | 1.00 | CA2 (0.43) | CA2ALDH1A1ALOX15TSHRLAP3 | |
| Phosphoric Acid SCHEMBL23630620 | 1.00 | CA2 (0.43) | CA2ALDH1A1ALOX15TSHRLAP3 | |
| Phosphoric Acid SCHEMBL3818781 | 1.00 | CA2 (0.43) | CA2ALDH1A1ALOX15TSHRLAP3 | |
| Phosphoric Acid SCHEMBL1574062 | 1.00 | — | — | |
| Phosphoric Acid SCHEMBL7196961 | 0.96 | CA2 (0.40) | CA2ALDH1A1ALOX15TSHRLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334485-A | Containing n-heterocyclic ring | THE CHROMALINE CORPORATION (US) | 1994-08-02 | — | — | US | claimed |
| US-5334485-A | Containing n-heterocyclic ring | THE CHROMALINE CORPORATION (US) | 1994-08-02 | — | — | US | disclosed |