Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GRK2 | P25098 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397596 | 1.00 | HTR1A (0.54) | HTR1AL3MBTL1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9397462 | 1.00 | HTR1A (0.54) | HTR1AL3MBTL1CYP3A4CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL1152347 | 0.99 | HTR1A (0.54) | HTR1AL3MBTL1CYP3A4CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL1152345 | 0.99 | HTR1A (0.54) | HTR1AL3MBTL1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL10431404 | 0.97 | HTR1A (0.53) | HTR1AL3MBTL1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL10431405 | 0.97 | HTR1A (0.53) | HTR1AL3MBTL1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL8604020 | 0.92 | L3MBTL1 (0.53) | HTR1AL3MBTL1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL8604024 | 0.92 | L3MBTL1 (0.53) | HTR1AL3MBTL1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL1151876 | 0.91 | L3MBTL1 (0.63) | HTR1AL3MBTL1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL7413959 | 0.91 | L3MBTL1 (0.52) | HTR1AL3MBTL1CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266574-B1 | Piperidine compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-01-05 | — | — | EP | claimed |
| EP-0374675-A2 | Reduction of piperidine-dion-derivatives and intermediates | NOVO NORDISK A/S (DK) | 1990-06-27 | — | — | EP | disclosed |