Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227811 | 0.90 | MAPT (0.37) | MAPTCACNA1BAPBA1NPSR1LMNA | |
| SCHEMBL9434734 | 0.90 | TSHR (0.43) | GABRR1GABRR2BLMNPSR1LMNA | |
| SCHEMBL9434744 | 0.90 | TSHR (0.43) | GABRR1GABRR2BLMNPSR1LMNA | |
| SCHEMBL28103576 | 0.85 | LMNA (0.31) | LMNA | |
| SCHEMBL28072502 | 0.83 | GABRR1 (0.31) | GABRR1GABRR2BLMNPSR1LMNA | |
| SCHEMBL489998 | 0.81 | — | — | |
| SCHEMBL460908 | 0.81 | — | — | |
| SCHEMBL22401702 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL28703257 | 0.79 | TSHR (0.42) | MAPTCACNA1BAPBA1LMNATSHR | |
| Fluoride SCHEMBL22583589 | 0.78 | GLRA1 (0.41) | GLRA1SLC6A9OR51E2GABRR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359128-A | Malic acid derivatives and compositions for the treatment of psoriasis | BLANK IZHAK (IL) | 1994-10-25 | — | — | US | disclosed |
| WO-1992012952-A1 | MALIC ACID DERIVATIVES AND COMPOSITIONS FOR THE TREATMENT OF PSORIASIS | DEXTER CHEMICAL CORPORATION (US) | 1992-08-06 | — | — | WO | disclosed |