Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397906 | 1.00 | NR1H4 (0.37) | NR1H4POLBMAPTPAX8RXRA | |
| SCHEMBL9397901 | 1.00 | NR1H4 (0.37) | NR1H4POLBMAPTPAX8RXRA | |
| SCHEMBL30159080 | 0.74 | POLB (0.32) | POLBMAPTRXRARXRBRXRG | |
| SCHEMBL30159039 | 0.74 | POLB (0.32) | POLBMAPTRXRARXRBRXRG | |
| SCHEMBL17440309 | 0.70 | NR1H4 (0.32) | NR1H4PAX8GPBAR1MAPK1 | |
| SCHEMBL17440235 | 0.70 | NR1H4 (0.32) | NR1H4PAX8GPBAR1MAPK1 | |
| SCHEMBL17440249 | 0.70 | NR1H4 (0.32) | NR1H4PAX8GPBAR1MAPK1 | |
| SCHEMBL18487409 | 0.69 | RXRA (0.36) | POLBMAPTRXRARXRBRXRG | |
| SCHEMBL15663190 | 0.67 | MAPK1 (0.32) | POLBMAPTRXRARXRBRXRG | |
| SCHEMBL19285732 | 0.66 | FFAR3 (0.37) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344845-A | Methyl 4(4-acetoxy-3-methoxycinnamanide and salts as an immunosuppressive drug for allergic reactions | TSUMURA & CO. (JP) | 1994-09-06 | — | — | US | disclosed |