Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | WRN | Q14191 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398147 | 0.83 | ALDH1A1 (0.61) | ALDH1A1NAAAFFAR3TSHR | |
| SCHEMBL8116737 | 0.83 | ALDH1A1 (0.44) | ALDH1A1CYP2C19 | |
| SCHEMBL5074549 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TDP1FFAR3MGAMGAA | |
| SCHEMBL11652667 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TDP1FFAR3MGAMGAA | |
| SCHEMBL17181554 | 0.73 | ALDH1A1 (0.33) | ALDH1A1NAAATDP1 | |
| SCHEMBL9276 | 0.73 | — | — | |
| SCHEMBL5075300 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TDP1TSHR | |
| SCHEMBL7152292 | 0.70 | ALDH1A1 (0.56) | ALDH1A1NAAATDP1FFAR3MGAM | |
| SCHEMBL9350570 | 0.70 | ALDH1A1 (0.56) | ALDH1A1NAAATDP1FFAR3MGAM | |
| Propane SCHEMBL20562580 | 0.70 | ALDH1A1 (0.56) | ALDH1A1NAAATDP1FFAR3MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354887-A | Reacting carbon monoxide and water with diacryloxylated butene in polar, aprotic solvent and catalyst | RHONE-POULENC CHIMIE (FR) | 1994-10-11 | — | — | US | disclosed |
| EP-0395545-B1 | PROCESS FOR PREPARING 1,6-HEXENEDIOIC ACIDS | RHONE-POULENC CHIMIE (FR) | 1993-07-28 | — | — | EP | disclosed |
| EP-0433189-B1 | PROCESS FOR THE PREPARATION OF DIESTERS OF HEXENEDIOIC ACID | RHONE-POULENC CHIMIE (FR) | 1993-06-23 | — | — | EP | disclosed |
| EP-0433190-B1 | PROCESS FOR PREPARING 1,6-HEXENDIOIC ACIDS | RHONE-POULENC CHIMIE (FR) | 1993-04-21 | — | — | EP | disclosed |
| EP-0347340-B1 | PROCESS FOR THE PREPARATION OF DIESTERS OF HEXENEDIOIC ACID | RHONE-POULENC CHIMIE (FR) | 1992-04-08 | — | — | EP | disclosed |
| US-5087735-A | Reacting carbon monoxide, alcohol and diacyloxylated butene in polar, aprotic solvent and catalyst system | RHONE-POULENC CHIMIE (FR) | 1992-02-11 | — | — | US | disclosed |
| US-5077433-A | Reacing carbon monoxide, water and diacyloxylated butene in th e presence of palladium and quaternary onium chloride | RHONE-POULENC CHIMIE (FR) | 1991-12-31 | — | — | US | disclosed |
| EP-0433190-A1 | Process for preparing 1,6-hexendioic acids | RHONE-POULENC CHIMIE (FR) | 1991-06-19 | — | — | EP | disclosed |
| EP-0433189-A1 | Process for the preparation of diesters of hexenedioic acid | RHONE-POULENC CHIMIE (FR) | 1991-06-19 | — | — | EP | disclosed |
| EP-0395545-A2 | Process for preparing 1,6-hexenedioic acids | RHONE-POULENC CHIMIE (FR) | 1990-10-31 | — | — | EP | disclosed |
| US-4925973-A | REACTION OF DIACETOXY BUTENE WITH ALCOHOL AND CARBON MONOXIDE | RHONE-POULENC CHIMIE (FR) | 1990-05-15 | — | — | US | disclosed |
| EP-0347340-A1 | Process for the preparation of diesters of hexenedioic acid | RHONE-POULENC CHIMIE (FR) | 1989-12-20 | — | — | EP | disclosed |
| EP-0009741-A1 | Process for the preparation of butenediol diesters | BASF Aktiengesellschaft (DE) | 1980-04-16 | — | — | EP | disclosed |