Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828102 | 0.79 | KDM4E (0.53) | TSHRALDH1A1KDM4EPOLBGAA | |
| SCHEMBL31422930 | 0.76 | IP6K1 (0.50) | ALDH1A1KDM4EPOLBGAAIP6K1 | |
| SCHEMBL9735507 | 0.75 | IP6K1 (0.51) | ALDH1A1KDM4EPOLBGAAIP6K1 | |
| SCHEMBL1082682 | 0.74 | MAPK1 (0.53) | EGLN1TSHRALDH1A1IP6K1HPGD | |
| SCHEMBL17475410 | 0.73 | KDM4E (0.51) | TSHRALDH1A1KDM4EPOLBGAA | |
| SCHEMBL31422910 | 0.73 | KDM4E (0.42) | ALDH1A1KDM4EPOLBGAAHPGD | |
| SCHEMBL31422970 | 0.73 | KDM4E (0.42) | ALDH1A1KDM4EPOLBGAAHPGD | |
| SCHEMBL1082894 | 0.72 | MAPK1 (0.51) | TSHRALDH1A1POLBGAAIP6K1 | |
| SCHEMBL31423132 | 0.72 | KDM4E (0.44) | ALDH1A1KDM4EPOLBGAAHPGD | |
| SCHEMBL29980141 | 0.72 | SLC16A3 (0.48) | ALDH1A1KDM4EPOLBGAAIP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332749-A | Bactericides | BOUCHARA (FR) | 1994-07-26 | — | — | US | disclosed |
| EP-0535184-A1 | NOVEL QUINOLONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | BOUCHARA S.A. (FR) | 1993-04-07 | — | — | EP | disclosed |
| EP-0533895-A1 | NOVEL QUINOLONES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOUCHARA S.A. (FR) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992017466-A1 | NOVEL QUINOLONES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOUCHARA S.A. (FR) | 1992-10-15 | — | — | WO | disclosed |
| WO-1992015574-A1 | NOVEL QUINOLONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | BOUCHARA S.A. (FR) | 1992-09-17 | — | — | WO | disclosed |