Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422910 | 1.00 | KDM4E (0.42) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31423132 | 0.95 | KDM4E (0.44) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL8828102 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31422770 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31273616 | 0.76 | ACMSD (0.49) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31423086 | 0.75 | CNR2 (0.39) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31423247 | 0.74 | CNR2 (0.40) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31423285 | 0.73 | ACMSD (0.52) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL9398264 | 0.73 | EGLN1 (0.45) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31422856 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1GAAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |