Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398644 | 0.96 | LMNA (0.45) | LMNAL3MBTL1EPHX2KMT2AMAPT | |
| SCHEMBL9191902 | 0.89 | RARB (0.42) | KMT2AMAPTMEN1RARBITGB3 | |
| SCHEMBL9017496 | 0.84 | RARB (0.52) | LMNAL3MBTL1EPHX2KMT2AMAPT | |
| SCHEMBL9590506 | 0.83 | LMNA (0.48) | LMNAL3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL9590499 | 0.83 | LMNA (0.48) | LMNAL3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL10363481 | 0.79 | CYP2C9 (0.53) | LMNAL3MBTL1EPHX2KMT2AMAPT | |
| SCHEMBL10363482 | 0.79 | CYP2C9 (0.53) | LMNAL3MBTL1EPHX2KMT2AMAPT | |
| SCHEMBL12611654 | 0.77 | LMNA (0.61) | LMNAL3MBTL1EPHX2KMT2AMAPT | |
| SCHEMBL9063261 | 0.77 | LMNA (0.63) | LMNAL3MBTL1EPHX2KMT2AMAPT | |
| SCHEMBL9857703 | 0.77 | LMNA (0.63) | LMNAL3MBTL1EPHX2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5346647-A | Cyclohexane compounds used in liquid crystalline mixtures | HOFFMANN-LA ROCHE INC. (US) | 1994-09-13 | — | — | US | disclosed |