Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857703 | 1.00 | LMNA (0.63) | LMNAL3MBTL1MAPTKMT2AGAA | |
| SCHEMBL5205374 | 0.89 | LMNA (0.63) | LMNAL3MBTL1MAPTKMT2AGAA | |
| SCHEMBL18562096 | 0.89 | LMNA (0.63) | LMNAL3MBTL1MAPTKMT2AGAA | |
| SCHEMBL11548487 | 0.89 | L3MBTL1 (0.63) | LMNAL3MBTL1MAPTKMT2AGAA | |
| SCHEMBL5789381 | 0.87 | LMNA (0.66) | LMNAL3MBTL1MAPTKMT2AGAA | |
| SCHEMBL11012644 | 0.87 | LMNA (0.70) | LMNAL3MBTL1MAPTKMT2AGAA | |
| SCHEMBL7692036 | 0.87 | L3MBTL1 (0.61) | LMNAL3MBTL1MAPTKMT2AGAA | |
| SCHEMBL9621303 | 0.87 | LMNA (0.66) | LMNAL3MBTL1MAPTKMT2AGAA | |
| SCHEMBL5112826 | 0.87 | LMNA (0.61) | LMNAL3MBTL1MAPTKMT2AGAA | |
| SCHEMBL2481397 | 0.87 | LMNA (0.66) | LMNAL3MBTL1MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407830-B1 | Polarizer | HOFFMANN LA ROCHE (CH) | 1996-09-25 | — | — | EP | disclosed |
| EP-0405346-B1 | Bistable ferroelectric liquid cristal display | HOFFMANN LA ROCHE (CH) | 1995-09-20 | — | — | EP | disclosed |