Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 2/20 | 0.39 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907946 | 0.87 | ALOX15 (0.51) | LMNAPGK1IGFBP5GSK3BMAP4K2 | |
| SCHEMBL2909922 | 0.86 | NQO2 (0.44) | NQO2PGK1GSK3BMAP4K2ALOX15 | |
| SCHEMBL27642242 | 0.78 | GRM2 (0.47) | NQO2GRM2LMNA | |
| SCHEMBL2910842 | 0.75 | ALOX15 (0.56) | LMNAIGFBP5ALOX15 | |
| SCHEMBL5717584 | 0.74 | GRM2 (0.55) | GRM2LMNA | |
| SCHEMBL1166903 | 0.74 | PDE4D (0.45) | NQO2GRM2EGFRKDRLMNA | |
| SCHEMBL2909590 | 0.74 | KMT2A (0.42) | EGFRKDRALOX15 | |
| SCHEMBL2904873 | 0.74 | NQO2 (0.48) | NQO2 | |
| SCHEMBL9398504 | 0.73 | PGK1 (0.36) | EGFRKDRPGK1GSK3BMAP4K2 | |
| SCHEMBL14514062 | 0.72 | GRM2 (0.53) | GRM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344922-A | 4-hydroxyquinaldic acid derivatives | BOARD OF REGENTS, UNIVERSITY OF TEXAS | 1994-09-06 | — | — | US | disclosed |
| US-5028707-A | 4-hydroxyquinaldic acid derivatives | BOARD OF REGENTS, UNIVERSITY OF TEXAS (US) | 1991-07-02 | — | — | US | disclosed |
| WO-1991007390-A1 | 4-HYDROXYQUINALDIC ACID DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-05-30 | — | — | WO | disclosed |