Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | PPM1D | O15297 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
| ▸ | NQO1 | P15559 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399506 | 0.87 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL9399242 | 0.87 | SRC (0.32) | NR1H2PPM1D | |
| SCHEMBL8108016 | 0.83 | NR1H2 (0.32) | NR1H2 | |
| SCHEMBL9595771 | 0.82 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL8107979 | 0.82 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL4293926 | 0.82 | NR1H2 (0.32) | NR1H2CCR2 | |
| SCHEMBL8759135 | 0.82 | NR1H2 (0.32) | NR1H2CCR2UCHL1 | |
| SCHEMBL4293924 | 0.82 | NR1H2 (0.32) | NR1H2CCR2 | |
| SCHEMBL9399785 | 0.81 | GPR119 (0.33) | NR1H2 | |
| SCHEMBL8112404 | 0.81 | NR1H2 (0.35) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374720-A | A thienamycins bactericides has nontoxic, side effect reduction against the kidney and central nervous system | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |