Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595744 | 0.81 | NR1H2 (0.36) | TSHRALDH1A1UCHL1 | |
| SCHEMBL9567154 | 0.81 | NR1H2 (0.36) | TSHRALDH1A1UCHL1 | |
| SCHEMBL9399973 | 0.77 | — | — | |
| SCHEMBL7860716 | 0.75 | ABCB1 (0.40) | — | |
| SCHEMBL9399220 | 0.75 | GCK (0.31) | ALDH1A1 | |
| SCHEMBL2708045 | 0.75 | UCHL1 (0.39) | UCHL1 | |
| SCHEMBL4300617 | 0.75 | UCHL1 (0.37) | TSHRALDH1A1UCHL1 | |
| SCHEMBL3832181 | 0.75 | UCHL1 (0.39) | UCHL1 | |
| SCHEMBL4300613 | 0.75 | UCHL1 (0.37) | TSHRALDH1A1UCHL1 | |
| SCHEMBL2809688 | 0.75 | UCHL1 (0.39) | UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374720-A | A thienamycins bactericides has nontoxic, side effect reduction against the kidney and central nervous system | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |