Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400132 | 0.85 | PTPN1 (0.49) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL13230464 | 0.80 | HTR1A (0.58) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL5176476 | 0.77 | CYP1A2 (0.48) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL7370108 | 0.76 | PTPN1 (0.67) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL1695394 | 0.75 | CACNA2D1 (0.52) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL7504880 | 0.75 | HTR1A (0.51) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL13113090 | 0.74 | MEN1 (0.79) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL4474966 | 0.74 | HTR1A (0.54) | PTPN1PTPN11HTR1AADRA1DADRA1A | |
| SCHEMBL329187 | 0.74 | KDM4E (0.51) | MEN1KMT2AGSK3BKDM4EALDH1A1 | |
| SCHEMBL27297227 | 0.74 | HTR1A (0.58) | PTPN1PTPN11HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5331006-A | Cholecystokinin, antisecretory agents | WARNER-LAMBERT COMPANY (US) | 1994-07-19 | — | — | US | disclosed |
| WO-1992004025-A1 | AMINO ACID ANALOGS AS CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |