SCHEMBL329187

SCHEMBL329187

CC(C)(Nc1cccc2ccccc12)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.51
RAB9A P51151 3/20 0.51
CYP3A4 P08684 2/20 0.51
NPC1 O15118 2/20 0.51
GAA P10253 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
MAPT P10636 2/20 0.50
ALDH1A1 P00352 3/20 0.49
HSD17B10 Q99714 3/20 0.49
MMP8 P22894 1/20 0.48
HPGD P15428 2/20 0.46
GSK3B P49841 1/20 0.46
CA12 O43570 1/20 0.46
CA4 P22748 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2721483 0.85 KDM4E (0.46) KDM4ERAB9ACYP3A4NPC1GAA
SCHEMBL28704036 0.83 KDM4E (0.53) KDM4ERAB9ACYP3A4NPC1GAA
Asparagine SCHEMBL6355509 0.83 KDM4E (0.43) KDM4ERAB9ACYP3A4NPC1GAA
SCHEMBL30904646 0.82 MMP8 (0.48) KDM4ERAB9ACYP3A4NPC1GAA
SCHEMBL8758916 0.81 RAB9A (0.46) KDM4ERAB9ACYP3A4NPC1GAA
SCHEMBL7270814 0.80 KDM4E (0.41) KDM4ERAB9ACYP3A4NPC1GAA
SCHEMBL8827773 0.79 KDM4E (0.41) KDM4ERAB9ACYP3A4NPC1CYP1A2
SCHEMBL31303189 0.77 IDO1 (0.55) KDM4ERAB9ACYP3A4NPC1GAA
SCHEMBL2622223 0.77 IDO1 (0.55) KDM4ERAB9ACYP3A4NPC1GAA
SCHEMBL4406254 0.77 RAB9A (0.52) KDM4ERAB9ANPC1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1678 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256172-B1 Method of treatment and agents useful for same THE UNIVERSITY OF MELBOURNE (AU) 2007-08-14 US claimed
US-7070969-B1 Plasmin inhibitors from the australian brown snake Pseudonaja textilis textilis THE UNIVERSITY OF QUEENSLAND (AU) 2006-07-04 US claimed
EP-4400164-A2 A METHOD OF INDUCING CARDIOMYOCYTES PROLIFERATION AND TREATING HEART DISEASES Yeda Research and Development Co. Ltd (IL) 2024-07-17 EP disclosed
EP-4400174-A2 IMMUNOREGULATORY MOLECULES AND USES THEREFOR The Francis Crick Institute Limited (GB) 2024-07-17 EP disclosed
WO-2024130161-A2 NOVEL CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF BIONECURE THERAPEUTICS INC (US) 2024-06-20 WO disclosed
US-20240190919-A1 PEPTIDE COMPOUNDS AND THERAPEUTIC USES OF SAME IMMUNITY PHARMA LTD. (IL) 2024-06-13 US disclosed
US-20240181020-A1 TREATMENT OF HYPOPARATHYROIDISM ENTERA BIO LTD. (IL) 2024-06-06 US disclosed
US-20240174730-A1 VARIANT FC DOMAINS AND USES THEREOF CIDARA THERAPEUTICS, INC. 2024-05-30 US disclosed
US-11986522-B2 Immunotherapeutic composition and uses thereof ARA VAX PTY LTD (AU) 2024-05-21 US disclosed
US-20240156975-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2024-05-16 US disclosed
US-11980658-B2 Immunotherapeutic molecules and uses thereof ARAVAX PTY LTD (AU) 2024-05-14 US disclosed
WO-1997015663-A1 A NOVEL HAEMOPOIETIN RECEPTOR AND GENETIC SEQUENCES ENCODING SAME AMRAD OPERATIONS PTY. LTD. (AU) 1997-05-01 WO disclosed
WO-1997012037-A1 A NOVEL HAEMOPOIETIN RECEPTOR AND GENETIC SEQUENCES ENCODING SAME AMRAD OPERATIONS PTY. LTD. (AU) 1997-04-03 WO disclosed
WO-1997005257-A1 PEPTIDE ANALOG INHIBITORS OF UROKINASE RECEPTOR ACTIVITY CHIRON CORPORATION (US) 1997-02-13 WO disclosed
WO-1997004091-A1 NOVEL RECEPTOR LIGANDS AND GENETIC SEQUENCES ENCODING SAME AMRAD OPERATIONS PTY. LTD. (AU) 1997-02-06 WO disclosed
EP-0745092-A1 PEPTIDE INHIBITORS OF UROKINASE RECEPTOR ACTIVITY CHIRON CORPORATION (US) 1996-12-04 EP disclosed
EP-0672049-A1 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS CHIRON MIMOTOPES PTY. LTD. (AU) 1995-09-20 EP disclosed
WO-1994028014-A2 PEPTIDE INHIBITORS OF UROKINASE RECEPTOR ACTIVITY CHIRON CORPORATION (US) 1994-12-08 WO disclosed
WO-1994011388-A1 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS CHIRON MIMOTOPES PTY. LTD. (AU) 1994-05-26 WO disclosed
WO-1994003483-A1 ENDOTHELIN RECEPTOR-BINDING COMPOUNDS CHIRON CORPORATION (US) 1994-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240181020-A1 TREATMENT OF HYPOPARATHYROIDISM PTH1R, PTMS, CYP24A1 KDM4E 1710/4885RAB9A 3480/4885CYP3A4 4548/4885
US-20240174730-A1 VARIANT FC DOMAINS AND USES THEREOF FCGR3B, FCGRT, FCGR2A KDM4E 1597/4885RAB9A 888/4885CYP3A4 2762/4885
US-20240156975-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A KDM4E 4753/4885RAB9A 1559/4885CYP3A4 995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.