Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 4/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.46 |
| ▸ | XDH | P47989 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399697 | 1.00 | IKBKE (0.46) | IKBKETBK1XDHALDH1A1HPGD | |
| SCHEMBL9398660 | 0.88 | ALDH1A1 (0.42) | IKBKETBK1XDHALDH1A1HPGD | |
| SCHEMBL9398668 | 0.88 | ALDH1A1 (0.42) | IKBKETBK1XDHALDH1A1HPGD | |
| SCHEMBL9398878 | 0.88 | ALDH1A1 (0.42) | IKBKETBK1XDHALDH1A1HPGD | |
| SCHEMBL9398868 | 0.88 | ALDH1A1 (0.42) | IKBKETBK1XDHALDH1A1HPGD | |
| SCHEMBL9399625 | 0.87 | XDH (0.43) | IKBKETBK1XDHALDH1A1HPGD | |
| SCHEMBL9399616 | 0.87 | XDH (0.43) | IKBKETBK1XDHALDH1A1HPGD | |
| SCHEMBL9399509 | 0.86 | IKBKE (0.38) | IKBKETBK1XDH | |
| SCHEMBL9399518 | 0.86 | IKBKE (0.38) | IKBKETBK1XDH | |
| SCHEMBL9399633 | 0.85 | GRM2 (0.45) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338483-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1994-08-16 | — | — | US | disclosed |
| US-5310501-A | Anisotropic compounds having Nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5227484-A | ANISOTROPIC COMPOUNDS HAVING NEMATIC PHASE AND LIQUID CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5179101-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1993-01-12 | — | — | US | disclosed |
| US-5047170-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4808333-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1989-02-28 | — | — | US | disclosed |
| EP-0084194-B1 | LIQUID CRYSTAL MIXTURES | MERCK PATENT GmbH (DE) | 1986-04-30 | — | — | EP | disclosed |
| EP-0084194-A1 | Liquid crystal mixtures | MERCK PATENT GmbH (DE) | 1983-07-27 | — | — | EP | disclosed |