SCHEMBL9400067

SCHEMBL9400067

Nc1ccccc1CCNC(=O)CCC(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.54
ALDH1A1 P00352 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.43
HDAC3 O15379 3/20 0.43
HDAC1 Q13547 3/20 0.43
HDAC2 Q92769 3/20 0.43
HDAC10 Q969S8 3/20 0.43
HDAC11 Q96DB2 3/20 0.43
HDAC8 Q9BY41 3/20 0.43
HDAC6 Q9UBN7 3/20 0.43
NCOR2 Q9Y618 3/20 0.43
HDAC4 P56524 2/20 0.43
HDAC9 Q9UKV0 2/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24405103 0.84 ALDH1A1 (0.53) ALDH1A1L3MBTL1KMT2AMAPK1
SCHEMBL21848124 0.83 LMNA (0.60) L3MBTL1MEN1KMT2AMAPTHDAC3
SCHEMBL12409525 0.79 HTT (0.62) TAAR1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL10785410 0.78 F13A1 (0.63) TAAR1L3MBTL1MEN1KMT2AHDAC3
SCHEMBL7301249 0.77 ALDH1A1 (0.51) TAAR1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL11448075 0.77 KMT2A (0.56) TAAR1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL11957306 0.76 HPGD (0.59) TAAR1ALDH1A1L3MBTL1MEN1KMT2A
Hydrochloric Acid SCHEMBL17335911 0.76 ALDH1A1 (0.50) TAAR1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL11447419 0.76 MEN1 (0.58) TAAR1ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL8797076 0.75 CA12 (0.46) ALDH1A1POLBHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5331006-A Cholecystokinin, antisecretory agents WARNER-LAMBERT COMPANY (US) 1994-07-19 US disclosed
WO-1992004025-A1 AMINO ACID ANALOGS AS CCK ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1992-03-19 WO disclosed