SCHEMBL9400293

SCHEMBL9400293

CCN1C(=O)c2c(Br)cc(Br)c(N)c2C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 5/20 0.41
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
USP2 O75604 1/20 0.34
ATM Q13315 1/20 0.34
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
MAPT P10636 2/20 0.33
GMNN O75496 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
THPO P40225 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MGLL Q99685 1/20 0.33
MAPK1 P28482 1/20 0.33
CLTC Q00610 1/20 0.33
POLB P06746 1/20 0.33
F2 P00734 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13376971 0.79 CASP3 (0.35) MEN1KMT2AMAPTTSHRGAA
SCHEMBL11704331 0.78 CYP1B1 (0.44) CYP1B1MEN1KMT2AUSP2ATM
SCHEMBL17146904 0.77 CYP1B1 (0.60) CYP1B1MEN1KMT2AUSP2ATM
SCHEMBL127891 0.73 CYP1B1 (0.56) CYP1B1MEN1KMT2AUSP2ATM
SCHEMBL128105 0.71 CYP1B1 (0.55) CYP1B1MEN1KMT2AUSP2ATM
SCHEMBL9156396 0.69 CYP1B1 (0.45) CYP1B1MEN1KMT2AUSP2ATM
SCHEMBL3684269 0.68 CYP1B1 (0.48) CYP1B1MEN1KMT2AUSP2ATM
SCHEMBL9170006 0.68 CA1 (0.44) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL5565610 0.68 CA1 (0.44) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL3692053 0.68 F2 (0.43) CYP1B1MAPTGMNNALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5290921-A Intermediates and colorants having primary hydroxyl enriched poly (oxyalkylene) moieties and their preparation MILLIKEN RESEARCH CORPORATION (US) 1994-03-01 US disclosed