SCHEMBL5565610

SCHEMBL5565610

Nc1c(Br)cc(Br)c2c1C(=O)c1c(Br)cc(Br)c(N)c1C2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.44
CA2 P00918 5/20 0.44
CA9 Q16790 5/20 0.44
CA3 P07451 1/20 0.44
FTO Q9C0B1 2/20 0.43
MAPT P10636 2/20 0.42
GAA P10253 1/20 0.42
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 2/20 0.36
POLB P06746 1/20 0.36
HTT P42858 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
THRB P10828 1/20 0.36
TSHR P16473 1/20 0.35
GSK3B P49841 1/20 0.34
CASP6 P55212 1/20 0.34
CYP3A4 P08684 1/20 0.33
CA12 O43570 1/20 0.31
CA4 P22748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9170006 1.00 CA1 (0.44) CA1CA2CA9CA3FTO
SCHEMBL17284186 0.89 CA1 (0.40) CA1CA2CA9CA3FTO
SCHEMBL11374348 0.84 FTO (0.42) CA1CA2CA9CA3FTO
1-Amino-2,4-Dibromoanthra-Quinone SCHEMBL3272427 0.83 FTO (0.64) FTOMAPTMEN1KMT2AALDH1A1
SCHEMBL18562218 0.83 THRB (0.46) CA1CA2CA9CA3FTO
SCHEMBL10488037 0.83 THRB (0.46) CA1CA2CA9CA3FTO
SCHEMBL10783253 0.79 CA1 (0.45) CA1CA2CA9CA3FTO
SCHEMBL5188106 0.79 CA1 (0.45) CA1CA2CA9CA3FTO
SCHEMBL10488055 0.78 FTO (0.47) CA1CA2CA9FTOMAPT
SCHEMBL10488045 0.78 FTO (0.47) CA1CA2CA9FTOMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-7160335-B2 Anthraquinone dyes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-09 US disclosed
US-20050177958-A1 Anthraquinone dyes HUNTSMAN INTERNATIONAL LLC 2005-08-18 US disclosed
CN-1643075-A Anthraquinone dyes CIBA SC HOLDING AG (CH) 2005-07-20 CN disclosed
EP-0353031-B1 Anthrapyridone compounds and their production process SUMITOMO CHEMICAL CO (JP) 1995-03-22 EP disclosed
US-5183892-A Used for coloring agent for synthetic resins and acid dyes; heat/light/sublimation and bleed resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-02-02 US disclosed
EP-0353031-A2 Anthrapyridone compounds and their production process SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-01-31 EP disclosed
US-4585574-A POSITIVE DIELECTRIC ANISOTROPY BAYER AKTIENGESELLSCHAFT (DE) 1986-04-29 US disclosed
EP-0008627-B1 QUINAZOLINE DERIVATIVES, AZO DYES DERIVED FROM THE QUINAZOLINES AND THEIR USE AS PIGMENTS BAYER AG (DE) 1984-10-03 EP disclosed
US-4389215-A Anthraquinone-azomethine compounds, processes for their preparation and processes for dyeing synthetic fibre materials and for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1983-06-21 US disclosed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US disclosed
US-4284411-A CONDENSATION, PIGMENTING BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
US-4261909-A Process for the reductive removal of halogen atoms from anthraquinones CIBA-GEIGY AG (CH) 1981-04-14 US disclosed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
EP-0023648-A1 Anthraquinone-azomethine compounds, process for their preparation; process for dyeing synthetic fibre materials as well as for pigmenting organic macromolecular materials BAYER AG (DE) 1981-02-11 EP disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
EP-0018538-A2 Anthraquinone derivatives, process for their preparation, process for the pigmentation of organic macromolecular materials and pigmented organic macromolecular material BAYER AG (DE) 1980-11-12 EP disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
EP-0008627-A2 Quinazoline derivatives, azo dyes derived from the quinazolines and their use as pigments BAYER AG (DE) 1980-03-19 EP disclosed
EP-0008063-A1 Azomethine derivatives of anthraquinones, methods for their preparation, their use in the pigmentation of organic macromolecular compounds and the materials thus obtained BAYER AG (DE) 1980-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050177958-A1 Anthraquinone dyes CHD8, AHR, CYB5R3 CA1 2672/4885CA2 1953/4885CA9 858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.