Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400335 | 1.00 | SLC6A3 (0.44) | SLC6A3SLC6A4MAPTMAPK1HTT | |
| SCHEMBL9400333 | 1.00 | SLC6A3 (0.44) | SLC6A3SLC6A4MAPTMAPK1HTT | |
| SCHEMBL9518943 | 0.89 | SLC6A3 (0.48) | SLC6A3SLC6A4MAPTMAPK1HTT | |
| SCHEMBL9518954 | 0.89 | SLC6A3 (0.48) | SLC6A3SLC6A4MAPTMAPK1HTT | |
| SCHEMBL9254794 | 0.85 | KDM4E (0.36) | SLC6A3SLC6A4MAPTKDM4EMEN1 | |
| SCHEMBL9254789 | 0.85 | KDM4E (0.36) | SLC6A3SLC6A4MAPTKDM4EMEN1 | |
| SCHEMBL9254792 | 0.85 | KDM4E (0.36) | SLC6A3SLC6A4MAPTKDM4EMEN1 | |
| SCHEMBL9580506 | 0.84 | SLC6A3 (0.46) | SLC6A3SLC6A4 | |
| SCHEMBL9580509 | 0.84 | SLC6A3 (0.46) | SLC6A3SLC6A4 | |
| SCHEMBL8967126 | 0.83 | RXRA (0.50) | SLC6A3SLC6A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326755-A | Contain cyclopropane ring | ROUSSEL UCLAF | 1994-07-05 | — | — | US | disclosed |