SCHEMBL9400337

SCHEMBL9400337

CCCCCCCCCCCCCCCCCC(=O)OC1CC(C)(C)N(OC(=O)C(=O)ON2C(C)(C)CC(OC(=O)CCCCCCCCCCCCCCCCC)CC2(C)C)C(C)(C)C1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.54
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43
DGKA P23743 1/20 0.39
PRKCA P17252 5/20 0.39
TSHR P16473 2/20 0.39
EPHX2 P34913 2/20 0.38
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1138686 0.93 NAAA (0.55) NAAAKMT2AMEN1GAADGKA
SCHEMBL10430889 0.90 NAAA (0.52) NAAAKMT2AMEN1GAADGKA
SCHEMBL1138932 0.90 NAAA (0.52) NAAAKMT2AMEN1GAADGKA
SCHEMBL12660726 0.89 NAAA (0.50) NAAAKMT2AMEN1GAADGKA
SCHEMBL10160236 0.87 NAAA (0.55) NAAAKMT2AMEN1GAADGKA
SCHEMBL28621432 0.86 KMT2A (0.48) NAAAKMT2AMEN1GAADGKA
SCHEMBL10465276 0.85 NAAA (0.52) NAAAKMT2AMEN1GAADGKA
SCHEMBL12201034 0.85 NAAA (0.52) NAAAKMT2AMEN1GAADGKA
SCHEMBL1638917 0.85 NAAA (0.52) NAAAKMT2AMEN1GAADGKA
SCHEMBL13435126 0.85 NAAA (0.52) NAAAKMT2AMEN1GAADGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300647-A Light stabilizers for polyolefins, other polymers CIBA-GEIGY CORPORATION (US) 1994-04-05 US claimed
US-5300647-A Light stabilizers for polyolefins, other polymers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
EP-0309400-B1 N-acyloxy hindered amine stabilizers CIBA GEIGY AG (CH) 1994-03-02 EP disclosed
US-5112890-A Piperidine compound with oxygen bonded to ring nitrogen CIBA-GEIGY CORPORATION (US) 1992-05-12 US disclosed
EP-0309400-A2 N-acyloxy hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed