SCHEMBL1138686

SCHEMBL1138686

CCCCCCCCCCCCCCCCCC(=O)OC1CC(C)(C)N(OC(=O)CCCCCCCCCCCCCCCCC)C(C)(C)C1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.55
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
GAA P10253 1/20 0.49
DGKA P23743 1/20 0.40
PRKCA P17252 5/20 0.39
TSHR P16473 2/20 0.39
EPHX2 P34913 2/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10430889 0.94 NAAA (0.52) NAAAKMT2AMEN1GAADGKA
SCHEMBL28621432 0.93 KMT2A (0.48) NAAAKMT2AMEN1GAADGKA
SCHEMBL9400337 0.93 NAAA (0.54) NAAAKMT2AMEN1GAADGKA
SCHEMBL1138932 0.92 NAAA (0.52) NAAAKMT2AMEN1GAADGKA
SCHEMBL1138999 0.92 KMT2A (0.58) NAAAKMT2AMEN1GAADGKA
SCHEMBL12660726 0.90 NAAA (0.50) NAAAKMT2AMEN1GAADGKA
SCHEMBL10160236 0.89 NAAA (0.55) NAAAKMT2AMEN1GAADGKA
SCHEMBL9745230 0.88 KMT2A (0.48) NAAAKMT2AMEN1GAAPRKCA
SCHEMBL3951982 0.86 NAAA (0.52) NAAAKMT2AMEN1GAADGKA
SCHEMBL13435126 0.86 NAAA (0.52) NAAAKMT2AMEN1GAADGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732168-B2 Method of preparing ethylene polymers by controlled high pressure polymerization BASF SE (DE) 2017-08-15 US disclosed
US-9732168-B2 Method of preparing ethylene polymers by controlled high pressure polymerization BASF SE (DE) 2017-08-15 US disclosed
US-20130150542-A1 Method Of Preparing Ethylene Polymers By Controlled High Pressure Polymerization BASF SE (DE) 2013-06-13 US disclosed
US-20130150542-A1 Method Of Preparing Ethylene Polymers By Controlled High Pressure Polymerization BASF SE (DE) 2013-06-13 US disclosed
EP-1655303-B1 Process for the Controlled Increase in Molecular Weight of Polyethylene or Polyethylene Blends BASF SE (DE) 2011-02-23 EP disclosed
US-7820248-B2 Coating composition comprising hydroxylamine esters CIBA SPECIALTY CHEMICALS CORP. (US) 2010-10-26 US disclosed
US-7820248-B2 Coating composition comprising hydroxylamine esters CIBA SPECIALTY CHEMICALS CORP. (US) 2010-10-26 US disclosed
US-20100210800-A1 METHOD OF PREPARING ETHYLENE POLYMERS BY CONTROLLED HIGH PRESSURE POLYMERIZATION CIBA CORPORATION (US) 2010-08-19 US disclosed
US-20100210800-A1 METHOD OF PREPARING ETHYLENE POLYMERS BY CONTROLLED HIGH PRESSURE POLYMERIZATION CIBA CORPORATION (US) 2010-08-19 US disclosed
US-7579411-B2 Process for the controlled increase in the molecular weight of polyethylenes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-08-25 US disclosed
US-7230042-B2 Flame retardant polymer compositions containing hydroxylamine esters CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-12 US disclosed
CN-1302002-C Hydroxylamine esters as polymerization initiators CIBA SC HOLDING AG (CH) 2007-02-28 CN disclosed
US-20060128903-A1 Process for the controlled increase in the molecular weight of polyethylenes ROTH MICHAEL 2006-06-15 US disclosed
EP-1282630-B1 Process for Reducing the Molecular Weight of Polypropylene Using Hydroxylamine Esters CIBA SC HOLDING AG (CH) 2006-05-10 EP disclosed
EP-1655303-A2 Hydroxylamine esters as polimerization initiators Ciba SC Holding AG (CH) 2006-05-10 EP disclosed
US-7030196-B2 Process for reducing the molecular weight of polypropylene CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-18 US disclosed
US-20030216494-A1 Hydroxylamine esters as polymerization initiators CIBA SPECIALTY CHEMICALS CORP. 2003-11-20 US disclosed
CN-1429229-A Hydroxylamine esters as polymerization initiators CIBA SC HOLDING AG (CH) 2003-07-09 CN disclosed
EP-1282630-A1 HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS Ciba SC Holding AG (CH) 2003-02-12 EP disclosed
WO-2001090113-A1 HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-11-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216494-A1 Hydroxylamine esters as polymerization initiators PNMT, HPGDS, HAAO NAAA 273/4885KMT2A 1030/4885MEN1 3964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.