Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.49 |
| ▸ | RIOK2 | Q9BVS4 | 5/20 | 0.47 |
| ▸ | GSK3A | P49840 | 3/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.47 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631803 | 0.80 | KCNH2 (0.58) | MEN1KMT2AL3MBTL1SMN1; SMN2GLA | |
| SCHEMBL24195991 | 0.79 | MEN1 (0.62) | NR1H4MEN1KMT2ANLRP3L3MBTL1 | |
| SCHEMBL22495484 | 0.78 | ALDH1A1 (0.64) | NR1H4MEN1KMT2ANLRP3L3MBTL1 | |
| SCHEMBL6890675 | 0.78 | MEN1 (0.55) | NR1H4MEN1KMT2ANLRP3L3MBTL1 | |
| SCHEMBL7822076 | 0.78 | NR1H4 (0.62) | NR1H4MEN1KMT2ANLRP3L3MBTL1 | |
| SCHEMBL7354818 | 0.78 | MEN1 (0.51) | NR1H4MEN1KMT2ANLRP3L3MBTL1 | |
| SCHEMBL11558110 | 0.77 | NR1H4 (0.39) | NR1H4MEN1KMT2ANLRP3L3MBTL1 | |
| SCHEMBL28372186 | 0.77 | MEN1 (0.65) | NR1H4MEN1KMT2ANLRP3L3MBTL1 | |
| SCHEMBL1520280 | 0.77 | MEN1 (0.65) | NR1H4MEN1KMT2ANLRP3L3MBTL1 | |
| SCHEMBL31713941 | 0.77 | NR1H4 (0.57) | NR1H4MEN1KMT2ANLRP3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332759-A | Treating a disorder due to vasodilation of the vascular system | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |
| US-3903163-A | N,N-Disubstituted naphthaleneacetamidines | DOW CHEMICAL CO | 1975-09-02 | — | — | US | disclosed |