Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520280 | 1.00 | MEN1 (0.65) | MEN1KMT2AHDAC8HDAC1HDAC3 | |
| SCHEMBL28869815 | 0.89 | NR1H4 (0.79) | MEN1KMT2AHDAC8HDAC1HDAC3 | |
| SCHEMBL24195991 | 0.87 | MEN1 (0.62) | MEN1KMT2AHDAC8HDAC1HDAC3 | |
| SCHEMBL28869800 | 0.87 | NLRP3 (0.73) | MEN1KMT2AHDAC8HDAC1HDAC3 | |
| SCHEMBL5848162 | 0.84 | L3MBTL1 (0.60) | MEN1KMT2ANR1H4NLRP3L3MBTL1 | |
| SCHEMBL31189138 | 0.84 | MEN1 (0.59) | MEN1KMT2AHDAC8HDAC1HDAC3 | |
| SCHEMBL2038480 | 0.82 | L3MBTL1 (0.76) | MEN1KMT2AHDAC8HDAC1HDAC3 | |
| SCHEMBL10362477 | 0.82 | HDAC1 (0.77) | HDAC8HDAC1HDAC3HDAC6HDAC2 | |
| SCHEMBL24196706 | 0.81 | MEN1 (0.56) | MEN1KMT2AHDAC8HDAC1HDAC3 | |
| SCHEMBL9367263 | 0.81 | NR1H4 (0.83) | MEN1KMT2AHDAC8HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522635-B | N-cyclopropyl nitrone derivatives and preparation method thereof | 东北师范大学 | 2020-02-14 | — | — | CN | disclosed |