Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759853 | 0.96 | MEN1 (0.41) | MAPTRAB9ASMN1; SMN2NPC1GFER | |
| SCHEMBL7761024 | 0.95 | MAPT (0.43) | MAPTRAB9ASMN1; SMN2NPC1GFER | |
| SCHEMBL9400504 | 0.93 | MEN1 (0.42) | MAPTRAB9ASMN1; SMN2NPC1GFER | |
| SCHEMBL9400440 | 0.91 | NPC1 (0.44) | MAPTRAB9ASMN1; SMN2NPC1GFER | |
| SCHEMBL9400401 | 0.91 | MAPT (0.44) | MAPTRAB9ASMN1; SMN2NPC1GFER | |
| SCHEMBL9400402 | 0.90 | MAPT (0.39) | MAPTRAB9ASMN1; SMN2NPC1GFER | |
| SCHEMBL9400379 | 0.90 | MAPT (0.45) | MAPTRAB9ASMN1; SMN2NPC1GFER | |
| SCHEMBL7760672 | 0.90 | MEN1 (0.44) | MAPTRAB9ASMN1; SMN2NPC1GFER | |
| Diethylamine SCHEMBL9400426 | 0.88 | RAB9A (0.39) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL9400452 | 0.88 | NPC1 (0.42) | MAPTRAB9ASMN1; SMN2NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372917-A | Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1994-12-13 | — | — | US | disclosed |