Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL27727311 | 0.84 | LMNA (0.56) | LMNATSHRALDH1A1FGFR4GABRP | |
| Isobutyramide SCHEMBL28681819 | 0.84 | LMNA (0.56) | LMNATSHRALDH1A1FGFR4GABRP | |
| Acrylic Acid SCHEMBL6928164 | 0.82 | LMNA (0.53) | LMNATSHRALDH1A1FGFR4GABRP | |
| SCHEMBL609764 | 0.81 | — | — | |
| SCHEMBL7519518 | 0.81 | — | — | |
| SCHEMBL7519648 | 0.81 | — | — | |
| Acrylamide SCHEMBL29204177 | 0.80 | ALDH1A1 (0.55) | LMNATSHRALDH1A1FGFR4GABRP | |
| Acrylic Acid SCHEMBL29625320 | 0.79 | LMNA (0.56) | LMNATSHRALDH1A1FGFR4GABRP | |
| Acrylic Acid SCHEMBL17458932 | 0.78 | — | — | |
| Acrylic Acid SCHEMBL6266430 | 0.78 | LMNA (0.62) | LMNATSHRALDH1A1FGFR4GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286893-A | Enzyme inhibitors for mixing with thienamycin(and derivatives) to prevent hydrolysis | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1994-02-15 | — | — | US | disclosed |
| US-5238930-A | Selective inactivators of renal dipeptidases | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1993-08-24 | — | — | US | disclosed |
| US-5112751-A | Inhibitors of enzymes which hydrolyze carbapenems | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1992-05-12 | — | — | US | disclosed |