Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 4/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50985 | 0.80 | — | — | |
| SCHEMBL6662073 | 0.75 | — | — | |
| SCHEMBL6670306 | 0.75 | — | — | |
| SCHEMBL1809603 | 0.71 | ALOX15 (0.57) | ALOX15HSD17B10TET2TET3TET1 | |
| SCHEMBL3992204 | 0.71 | — | — | |
| SCHEMBL4579976 | 0.70 | ALOX15 (0.58) | ALOX15HSD17B10TET2TET3TET1 | |
| SCHEMBL10061456 | 0.70 | ALOX15 (0.46) | ALOX15HSD17B10TET2TET3TET1 | |
| Itaconate SCHEMBL8068645 | 0.69 | ALOX15 (0.71) | ALOX15HSD17B10TET2TET3TET1 | |
| SCHEMBL8618420 | 0.69 | TDP1 (0.45) | ALOX15HSD17B10TET2TET3TET1 | |
| SCHEMBL16798172 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286893-A | Enzyme inhibitors for mixing with thienamycin(and derivatives) to prevent hydrolysis | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1994-02-15 | — | — | US | claimed |
| US-5238930-A | Selective inactivators of renal dipeptidases | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1993-08-24 | — | — | US | claimed |