Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027438 | 0.98 | MAPT (0.45) | MAPTTP53THRBRAB9ANPC1 | |
| SCHEMBL9029415 | 0.94 | MAPT (0.45) | MAPTTP53RAB9ANPC1CASP3 | |
| SCHEMBL9401101 | 0.93 | MAPT (0.44) | MAPTTP53THRBRAB9ANPC1 | |
| SCHEMBL9401171 | 0.93 | MAPT (0.56) | MAPTTHRBRAB9ANPC1ALDH1A1 | |
| SCHEMBL9028732 | 0.89 | EIF4E (0.44) | MAPTTP53THRBRAB9ANPC1 | |
| SCHEMBL9027009 | 0.86 | MAPT (0.45) | MAPTTP53THRBRAB9ANPC1 | |
| SCHEMBL9401114 | 0.83 | MAPT (0.32) | MAPTKDM4E | |
| SCHEMBL9026772 | 0.77 | MAPT (0.46) | MAPTTP53THRBRAB9ANPC1 | |
| SCHEMBL9028748 | 0.76 | ALDH1A1 (0.36) | ALDH1A1DHODH | |
| SCHEMBL9027887 | 0.75 | MAPT (0.40) | MAPTRAB9ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310746-A | Insecticides, miticides, nematocides | ROUSSEL UCLAF (FR) | 1994-05-10 | — | — | US | disclosed |