Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401102 | 0.93 | MAPT (0.46) | MAPTTP53THRBALDH1A1MEN1 | |
| SCHEMBL9027438 | 0.93 | MAPT (0.45) | MAPTTP53THRBALDH1A1LMNA | |
| SCHEMBL9029415 | 0.92 | MAPT (0.45) | MAPTTP53ALDH1A1LMNAMEN1 | |
| SCHEMBL9401171 | 0.91 | MAPT (0.56) | MAPTTHRBALDH1A1MEN1KMT2A | |
| SCHEMBL9028732 | 0.86 | EIF4E (0.44) | MAPTTP53THRBMEN1KMT2A | |
| SCHEMBL9027009 | 0.81 | MAPT (0.45) | MAPTTP53THRBALDH1A1LMNA | |
| SCHEMBL9401114 | 0.81 | MAPT (0.32) | MAPTCYP1A2KDM4ECYP2D6CYP2C9 | |
| SCHEMBL9029323 | 0.79 | MAPT (0.41) | MAPTTP53THRBALDH1A1LMNA | |
| SCHEMBL9028748 | 0.77 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL9026772 | 0.75 | MAPT (0.46) | MAPTTP53THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310746-A | Insecticides, miticides, nematocides | ROUSSEL UCLAF (FR) | 1994-05-10 | — | — | US | disclosed |