Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 3/20 | 0.34 |
| ▸ | EDNRA | P25101 | 3/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401653 | 0.88 | EDNRB (0.42) | EDNRBEDNRAMAPTTDP1L3MBTL1 | |
| SCHEMBL9401605 | 0.85 | EDNRB (0.33) | EDNRBEDNRA | |
| SCHEMBL9401350 | 0.84 | EDNRB (0.41) | EDNRBEDNRACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL9401408 | 0.83 | EDNRB (0.36) | EDNRBEDNRACASRCYP3A4CYP2D6 | |
| SCHEMBL9401569 | 0.83 | EDNRB (0.34) | EDNRBEDNRA | |
| SCHEMBL9401423 | 0.83 | ALOX5 (0.32) | EDNRBEDNRAL3MBTL1 | |
| SCHEMBL9572233 | 0.83 | PTGES (0.40) | EDNRBEDNRAMAPT | |
| SCHEMBL9401461 | 0.83 | EDNRB (0.42) | EDNRBEDNRASMN1; SMN2 | |
| SCHEMBL9401292 | 0.83 | EDNRB (0.41) | EDNRBEDNRA | |
| SCHEMBL9401625 | 0.81 | NPSR1 (0.34) | EDNRBEDNRASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5346880-A | Pre- and postemergence | NIHON BAYER AGROCHEM K.K. (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0565951-A1 | Herbicidally active pyrimidinylthioalkane derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1993-10-20 | — | — | EP | disclosed |