Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401431 | 1.00 | CA1 (0.54) | CA1CA2CA4CA7ALDH1A1 | |
| SCHEMBL77601 | 0.91 | MAPT (0.53) | ALDH1A1KDM4EMAPTGSK3BHPGD | |
| SCHEMBL8038651 | 0.89 | ALDH1A1 (0.62) | CA1CA2CA4CA7ALDH1A1 | |
| SCHEMBL5645074 | 0.86 | THRB (0.50) | ALDH1A1KDM4EMAPTGSK3BHPGD | |
| SCHEMBL1514195 | 0.86 | THRB (0.50) | ALDH1A1KDM4EMAPTGSK3BHPGD | |
| SCHEMBL14273770 | 0.85 | GSK3B (0.47) | CA1CA2CA4CA7ALDH1A1 | |
| SCHEMBL10353052 | 0.84 | KDM4E (0.52) | ALDH1A1KDM4ETDP1GAAMAPT | |
| SCHEMBL9401645 | 0.84 | KDM4E (0.52) | ALDH1A1KDM4ETDP1GAAMAPT | |
| SCHEMBL6508831 | 0.84 | ALDH1A1 (0.72) | CA1CA2CA7ALDH1A1KDM4E | |
| SCHEMBL9401639 | 0.84 | KDM4E (0.52) | ALDH1A1KDM4ETDP1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |
| EP-0380585-A1 | PROCESS FOR PREPARING 2-NAPHTHANOIC ACIDS AND ESTERS THEREOF | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-08-08 | — | — | EP | disclosed |
| WO-1989003377-A1 | PROCESS FOR PREPARING 2-NAPHTHANOIC ACIDS AND ESTERS THEREOF | EASTMAN KODAK COMPANY (US) | 1989-04-20 | — | — | WO | disclosed |
| US-4761497-A | Process for preparing 2-naphthanoic acids and esters thereof | EASTMAN KODAK COMPANY (US) | 1988-08-02 | — | — | US | disclosed |