Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835842 | 0.87 | ADORA3 (0.72) | TSHRALDH1A1KDM4EHSD17B10HTT | |
| SCHEMBL7265410 | 0.86 | TSHR (0.65) | TSHRALDH1A1KDM4EHSD17B10HTT | |
| SCHEMBL6951320 | 0.84 | ADORA3 (0.76) | TSHRALDH1A1KDM4EHSD17B10HTT | |
| SCHEMBL9401767 | 0.83 | KDM4E (0.68) | TSHRALDH1A1KDM4EHSD17B10HTT | |
| SCHEMBL9272854 | 0.83 | CACNA1F (0.69) | TSHRALDH1A1KDM4EHSD17B10HTT | |
| SCHEMBL7158395 | 0.82 | ADORA3 (0.60) | TSHRALDH1A1KDM4EHSD17B10HTT | |
| SCHEMBL7358894 | 0.81 | TSHR (0.67) | TSHRALDH1A1KDM4EHSD17B10HTT | |
| SCHEMBL3118761 | 0.81 | CACNA1F (0.59) | TSHRALDH1A1KDM4EHSD17B10HTT | |
| SCHEMBL7162679 | 0.80 | TSHR (0.58) | TSHRALDH1A1KDM4EHSD17B10HTT | |
| SCHEMBL9832868 | 0.80 | CACNA1B (0.70) | HTTADORA3KMT2AMEN1CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |