Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.54 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817128 | 0.94 | KDM4E (0.76) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL27517088 | 0.93 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL3218696 | 0.89 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7265410 | 0.88 | TSHR (0.65) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL6951320 | 0.87 | ADORA3 (0.76) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL28735887 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL9272854 | 0.86 | CACNA1F (0.69) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7236402 | 0.85 | ALDH1A1 (0.60) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7158395 | 0.84 | ADORA3 (0.60) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL7275646 | 0.84 | CACNA1F (0.71) | KDM4EALDH1A1GAAHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |