Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401777 | 0.95 | CYP11B1 (0.44) | CYP11B1CYP17A1CYP21A2CYP19A1TBXAS1 | |
| SCHEMBL9401775 | 0.86 | CACNA1B (0.51) | CYP11B1CYP17A1CYP21A2CYP19A1TBXAS1 | |
| SCHEMBL9401787 | 0.86 | CACNA1B (0.51) | CYP11B1CYP17A1CYP21A2CYP19A1TBXAS1 | |
| SCHEMBL9401791 | 0.83 | CYP17A1 (0.41) | CYP11B1CYP17A1CYP21A2CYP19A1TBXAS1 | |
| SCHEMBL9401783 | 0.82 | CACNA1B (0.56) | CYP11B1CYP17A1CYP21A2CYP19A1TBXAS1 | |
| SCHEMBL9401773 | 0.82 | CACNA1B (0.56) | CYP11B1CYP17A1CYP21A2CYP19A1TBXAS1 | |
| SCHEMBL9401969 | 0.81 | CACNA1B (0.56) | CYP11B1CYP17A1CYP21A2CYP19A1TBXAS1 | |
| SCHEMBL9401782 | 0.81 | CACNA1B (0.56) | CYP11B1CYP17A1CYP21A2CYP19A1TBXAS1 | |
| SCHEMBL9401841 | 0.81 | CACNA1B (0.56) | CYP11B1CYP17A1CYP21A2CYP19A1TBXAS1 | |
| SCHEMBL9833247 | 0.79 | CACNA1B (0.59) | CYP1A2LMNACYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |