Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.59 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MLNR | O43193 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401777 | 0.84 | CYP11B1 (0.44) | CACNA1BCACNA1CKMT2AMEN1ADORA3 | |
| SCHEMBL3443986 | 0.84 | CYP1A2 (0.55) | CACNA1BCACNA1CKMT2AMEN1ADORA3 | |
| SCHEMBL30873727 | 0.81 | CYP1A2 (0.57) | CACNA1BCACNA1CKMT2AMEN1ADORA3 | |
| SCHEMBL5396699 | 0.81 | CYP1A2 (0.48) | CACNA1BCACNA1CKMT2AMEN1ADORA3 | |
| SCHEMBL5396705 | 0.81 | CYP1A2 (0.48) | CACNA1BCACNA1CKMT2AMEN1ADORA3 | |
| SCHEMBL20801670 | 0.81 | CYP1A2 (0.55) | CACNA1BCACNA1CKMT2AMEN1ADORA3 | |
| SCHEMBL8403732 | 0.80 | MAPT (0.50) | CACNA1BCACNA1CKMT2AMEN1ADORA3 | |
| SCHEMBL28408223 | 0.80 | LMNA (0.58) | CACNA1BCACNA1CKMT2AMEN1ADORA3 | |
| SCHEMBL6534522 | 0.80 | CACNA1C (0.69) | CACNA1BCACNA1CKMT2AMEN1ADORA3 | |
| SCHEMBL10656803 | 0.80 | CACNA1F (0.53) | CACNA1BCACNA1CKMT2AMEN1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161877-B1 | 1,4-DIHYDROPYRIDINE DERIVATIVES, METHODS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1991-05-29 | — | — | EP | claimed |