Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.69 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.69 |
| ▸ | AGT | P01019 | 2/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402029 | 0.93 | AGTR1 (0.59) | AGTR1AGTR2AGTPDE4APDE4B | |
| SCHEMBL9402014 | 0.88 | AGTR1 (0.57) | AGTR1AGTR2AGT | |
| SCHEMBL9851487 | 0.87 | AGTR1 (0.63) | AGTR1AGTR2AGTPDE4APDE4B | |
| SCHEMBL9311665 | 0.86 | AGT (0.69) | AGTR1AGTR2AGT | |
| SCHEMBL9402064 | 0.86 | AGTR1 (0.55) | AGTR1AGTR2AGTPPARG | |
| SCHEMBL9404590 | 0.85 | AGT (0.69) | AGTR1AGTR2AGT | |
| SCHEMBL9295555 | 0.85 | AGT (0.69) | AGTR1AGTR2AGT | |
| SCHEMBL9402043 | 0.85 | AGTR1 (0.55) | AGTR1AGTR2AGT | |
| SCHEMBL9851417 | 0.85 | AGTR1 (0.63) | AGTR1AGTR2AGTPPARG | |
| SCHEMBL9402070 | 0.85 | AGTR1 (0.54) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304565-A | Angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0445811-A2 | Nitrogen-containing heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-09-11 | — | — | EP | disclosed |