Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.57 |
| ▸ | AGT | P01019 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402029 | 0.90 | AGTR1 (0.59) | AGTR1AGTR2AGTALDH1A1MEN1 | |
| SCHEMBL9402070 | 0.89 | AGTR1 (0.54) | AGTR1AGTR2AGTALDH1A1MEN1 | |
| SCHEMBL9402017 | 0.88 | AGTR1 (0.69) | AGTR1AGTR2AGT | |
| SCHEMBL9402064 | 0.88 | AGTR1 (0.55) | AGTR1AGTR2AGTALDH1A1MEN1 | |
| SCHEMBL9402043 | 0.87 | AGTR1 (0.55) | AGTR1AGTR2AGTALDH1A1MEN1 | |
| SCHEMBL9851456 | 0.86 | AGTR1 (0.52) | AGTR1AGTR2AGTLMNAPOLB | |
| SCHEMBL9265478 | 0.83 | AGTR1 (0.56) | AGTR1AGTR2AGTALDH1A1MEN1 | |
| SCHEMBL9263837 | 0.81 | AGT (0.57) | AGTR1AGTR2AGT | |
| SCHEMBL9851445 | 0.79 | AGTR1 (0.53) | AGTR1AGTR2AGTSMN1; SMN2RAB9A | |
| SCHEMBL13679193 | 0.78 | AGTR1 (0.55) | AGTR1AGTR2AGTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304565-A | Angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0445811-A2 | Nitrogen-containing heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-09-11 | — | — | EP | disclosed |