SCHEMBL9402295

SCHEMBL9402295

O=C1CN(CC2NC(=O)NC2=O)C(=O)N1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADAMTS5 Q9UNA0 6/20 0.33
ADAMTS4 O75173 2/20 0.33
GAA P10253 1/20 0.33
TSHR P16473 2/20 0.32
CRBN Q96SW2 1/20 0.32
ADAM17 P78536 2/20 0.32
ADAM10 O14672 1/20 0.32
MMP12 P39900 1/20 0.32
ADAM9 Q13443 1/20 0.32
MMP2 P08253 1/20 0.30
HDAC8 Q9BY41 2/20 0.30
RGS12 O14924 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12004346 0.71 CRBN (0.38) GAACRBN
SCHEMBL544564 0.68 TP53 (0.48) CRBN
SCHEMBL13127158 0.68
SCHEMBL13127072 0.68
SCHEMBL8999579 0.67 CRBN (0.46) GAACRBN
SCHEMBL11352404 0.67 TSHR (0.46) ADAMTS5ADAMTS4GAATSHRADAM17
SCHEMBL17186322 0.67 ADAMTS5 (0.40) ADAMTS5ADAMTS4GAAADAM17ADAM10
SCHEMBL854739 0.65
SCHEMBL25808010 0.65 CRBN (0.44) CRBN
SCHEMBL27584542 0.65 TSHR (0.39) ADAMTS5ADAMTS4GAATSHRADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE34768-E Having N-heterocyclic chain extending groups, also with polyfunctional and bromine-containing epoxy resins, curing agents and accelerators, for fireproof, heat resistant, nondeforming printed circuits INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1994-10-25 US disclosed
US-5130407-A Modified epoxy resins for printed circuits and electronics INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1992-07-14 US disclosed
US-5006615-A Printed circuit INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1991-04-09 US disclosed