Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402524 | 0.94 | HDAC3 (0.52) | NPC1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL9402875 | 0.93 | PTPN11 (0.54) | LRRK2 | |
| SCHEMBL9402538 | 0.93 | PTPN11 (0.54) | LRRK2 | |
| SCHEMBL9402671 | 0.93 | PTPN11 (0.54) | LRRK2 | |
| SCHEMBL9324880 | 0.90 | PTPN11 (0.51) | NPC1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL11563262 | 0.90 | MAOB (0.56) | NPC1KDM4ELMNARAB9ALRRK2 | |
| SCHEMBL9402635 | 0.87 | FOLH1 (0.59) | NPC1KDM4ERAB9AHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9402840 | 0.86 | FOLH1 (0.58) | NPC1KDM4ERAB9AHTTSMN1; SMN2 | |
| SCHEMBL9402836 | 0.85 | MGLL (0.48) | NPC1KDM4ERAB9AHTTSMN1; SMN2 | |
| SCHEMBL22438874 | 0.84 | PTPN11 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298652-A | N-substituted glycines, inhibitors of phospholipase A2 | HOFFMANN-LA ROCHE INC. (US) | 1994-03-29 | — | — | US | disclosed |