SCHEMBL9403286

SCHEMBL9403286

CCCC(=O)C(=O)Oc1ccc(C)cc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
KMT2A Q03164 5/20 0.49
BCL9 O00512 1/20 0.46
CTNNB1 P35222 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
GAA P10253 1/20 0.44
MEN1 O00255 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
ELANE P08246 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1289930 0.84 ELANE (0.46) LMNAKMT2ABCL9CTNNB1MEN1
SCHEMBL1088831 0.83 CES2 (0.53) KMT2ABCL9CTNNB1L3MBTL1MEN1
SCHEMBL898796 0.81 BCL9 (0.62) LMNAKMT2ABCL9CTNNB1L3MBTL1
SCHEMBL161868 0.80 BCL9 (0.74) LMNAKMT2ABCL9CTNNB1GAA
SCHEMBL7064531 0.80 LMNA (0.70) LMNAKMT2AL3MBTL1GAAALDH1A1
Toluene SCHEMBL27972648 0.78 CES2 (0.50) KMT2AL3MBTL1MEN1CES2CES1
SCHEMBL13213492 0.77 LMNA (0.47) LMNAKMT2AL3MBTL1GAAMEN1
SCHEMBL7064350 0.77 LMNA (0.55) LMNAKMT2AL3MBTL1GAAMEN1
SCHEMBL6689929 0.74 KMT2A (0.57) LMNAKMT2ABCL9CTNNB1L3MBTL1
SCHEMBL7553867 0.74 LMNA (0.61) LMNAKMT2AL3MBTL1GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6157488-A None JP disclosed
JP-H06157488-A OXAZOLIDIN-2,4-DIONE DERIVATIVE, PRODUCTION THEREOF AND NONLINEAR OPTICAL MATERIAL COMPOSED OF THE SAME SAGAMI CHEM RES CENTER 1994-06-03 JP disclosed