Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 4/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9403441 | 0.80 | KMT2A (0.42) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL6793329 | 0.80 | MEN1 (0.62) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL1699164 | 0.80 | NPC1 (0.65) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL5322748 | 0.72 | HSP90AA1 (0.59) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL3919788 | 0.70 | MAPK1 (0.63) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL9403360 | 0.69 | BRD4 (0.58) | MEN1KMT2ANPC1RAB9AALOX5 | |
| SCHEMBL5579639 | 0.69 | CTSV (0.55) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL5580003 | 0.69 | CTSV (0.57) | MEN1KMT2ANPC1RAB9AATM | |
| Hydrochloric Acid SCHEMBL8808091 | 0.69 | EGFR (0.59) | MEN1KMT2ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL30832846 | 0.69 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338740-A | Angiotensin II receptor antagonists | PFIZER INC. (US) | 1994-08-16 | — | — | US | disclosed |