Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 20/20 | 0.33 |
| ▸ | FNTB | P49356 | 20/20 | 0.33 |
| ▸ | HRAS | P01112 | 1/20 | 0.32 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18650419 | 0.79 | AKR1B1 (0.34) | FNTAFNTB | |
| SCHEMBL30849376 | 0.78 | OPRL1 (0.36) | — | |
| SCHEMBL30702209 | 0.78 | HTT (0.35) | FNTAFNTBHRASKRASABCB1 | |
| SCHEMBL30856753 | 0.78 | FNTA (0.33) | FNTAFNTBHRASKRASABCB1 | |
| SCHEMBL14616893 | 0.78 | HTT (0.35) | FNTAFNTBHRASKRASABCB1 | |
| SCHEMBL14616897 | 0.78 | FNTA (0.33) | FNTAFNTBHRASKRASABCB1 | |
| SCHEMBL30702240 | 0.78 | FNTA (0.33) | FNTAFNTBHRASKRASABCB1 | |
| SCHEMBL17942179 | 0.73 | MAP4K4 (0.35) | FNTAFNTBHRASKRASABCB1 | |
| SCHEMBL21499843 | 0.72 | FNTA (0.37) | FNTAFNTBHRASKRASABCB1 | |
| SCHEMBL10287035 | 0.71 | POLB (0.36) | FNTAFNTBHRASKRASABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11845748-B2 | Bicyclic pyridine N-oxide derivatives useful as a factor XIa inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2023-12-19 | — | — | US | disclosed |
| US-11814364-B2 | Pyridine N-oxide derivatives useful as factor XIa inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-14 | — | — | US | disclosed |
| US-11814364-B2 | Pyridine N-oxide derivatives useful as factor XIa inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-14 | — | — | US | disclosed |
| US-20220306632-A1 | BICYCLIC PYRIDINE N-OXIDE DERIVATIVES USEFUL AS A FACTOR XIA INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-09-29 | — | — | US | disclosed |
| WO-2017188288-A1 | 5-SUBSTITUTED AZABENZIMIDAZOLE DERIVATIVE HAVING AMPK ACTIVATION ACTION | 塩野義製薬株式会社 | 2017-11-02 | — | — | WO | disclosed |
| US-5338740-A | Angiotensin II receptor antagonists | PFIZER INC. (US) | 1994-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306632-A1 | BICYCLIC PYRIDINE N-OXIDE DERIVATIVES USEFUL AS A FACTOR XIA INHIBITORS | F2, F11, KLKB1 | FNTA 1448/4885FNTB 1477/4885HRAS 4027/4885 |
| US-11845748-B2 | Bicyclic pyridine N-oxide derivatives useful as a factor XIa inhibitors | F2, F11, KLKB1 | FNTA 1448/4885FNTB 1477/4885HRAS 4027/4885 |
| US-11814364-B2 | Pyridine N-oxide derivatives useful as factor XIa inhibitors | F11, F2, KLKB1 | FNTA 1126/4885FNTB 1470/4885HRAS 3798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.