Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.33 |
| ▸ | FNTB | P49356 | 18/20 | 0.33 |
| ▸ | HRAS | P01112 | 1/20 | 0.32 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GFRA3 | O60609 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616897 | 1.00 | FNTA (0.33) | FNTAFNTBHRASKRASABCB1 | |
| SCHEMBL30856753 | 1.00 | FNTA (0.33) | FNTAFNTBHRASKRASABCB1 | |
| SCHEMBL10287035 | 0.89 | POLB (0.36) | FNTAFNTBHRASKRASABCB1 | |
| SCHEMBL18650419 | 0.79 | AKR1B1 (0.34) | FNTAFNTBHTTKMT2A | |
| SCHEMBL24729873 | 0.78 | GFRA3 (0.31) | GFRA3RET | |
| SCHEMBL12696395 | 0.78 | EPAS1 (0.34) | GFRA3RET | |
| SCHEMBL568654 | 0.78 | TRPM5 (0.36) | FNTAFNTBGFRA3RET | |
| SCHEMBL23937987 | 0.78 | DRD2 (0.36) | FNTAFNTBGFRA3RET | |
| SCHEMBL14616893 | 0.78 | HTT (0.35) | FNTAFNTBHRASKRASABCB1 | |
| SCHEMBL9403366 | 0.78 | FNTA (0.33) | FNTAFNTBHRASKRASABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594307-A1 | 1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2025-08-06 | — | — | EP | disclosed |
| CN-117964573-A | Dihydrobenzofuran and indene analogs as myocardial segment inhibitors | 赛特凯恩蒂克公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117924208-A | Dihydrobenzofuran and indene analogs as myocardial segment inhibitors | 赛特凯恩蒂克公司 | 2024-04-26 | — | — | CN | disclosed |
| WO-2024073426-A1 | 1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| CN-111757875-B | Dihydrobenzofuran and indene analogs as myocardial segment inhibitors | 赛特凯恩蒂克公司 | 2024-01-09 | — | — | CN | disclosed |