Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498638 | 0.86 | CA2 (0.58) | CA2POLBCA12CA1CA9 | |
| SCHEMBL8951864 | 0.84 | MAPT (0.45) | CA2MAPTNPSR1CA12CA1 | |
| SCHEMBL7029931 | 0.84 | CA2 (0.53) | CA2POLBLOXCCR2MEN1 | |
| SCHEMBL3369801 | 0.84 | CA2 (0.60) | CA2MAPTPOLBCA12CA1 | |
| SCHEMBL9178626 | 0.81 | MAPT (0.40) | CA2MAPTNPSR1CA12CA1 | |
| SCHEMBL5677264 | 0.81 | CA2 (0.61) | CA2MAPTPOLBCA12CA1 | |
| SCHEMBL10606415 | 0.81 | CA2 (0.81) | CA2MAPTPOLBCA12CA1 | |
| SCHEMBL10693250 | 0.80 | GAA (0.52) | CA2MAPTNPSR1POLBCA12 | |
| SCHEMBL11400330 | 0.80 | MAPT (0.47) | CA2MAPTNPSR1CA12CA1 | |
| SCHEMBL11323062 | 0.80 | CA2 (0.43) | CA2MAPTNPSR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295527-B1 | Process for the preparation of 3-aminophenyl-2-hydroxyethylsulfon | BAYER AG (DE) | 1994-03-02 | — | — | EP | disclosed |
| EP-0387531-B1 | PROCESS FOR THE PREPARATION OF BETA-CHLOROETHYL SULFONYL ARYL ISOCYANATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0384265-B1 | PROCESS FOR THE PREPARATION OF BETA-CHLOROETHYL SULFONYL ARYL ISOCYANATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-31 | — | — | EP | disclosed |
| EP-0387531-A1 | Process for the preparation of beta-chloroethyl sulfonyl aryl isocyanates | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-19 | — | — | EP | disclosed |
| EP-0384265-A1 | Process for the preparation of beta-chloroethyl sulfonyl aryl isocyanates | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| US-4948917-A | REACTING PHOSGENE AND BETA-HYDROXYETHYLSULFONYL-ARYLAMINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-14 | — | — | US | disclosed |
| US-4929757-A | Process for the preparation of 3-aminophenyl 2-hydroxy-ethyl sulphone | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-29 | — | — | US | disclosed |