SCHEMBL10693250

SCHEMBL10693250

CCS(=O)(=O)c1ccc(Cl)c(N)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.52
MAPT P10636 3/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PSIP1 O75475 2/20 0.46
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
PKM P14618 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9806947 0.85 CA1 (0.63) GAAPSIP1CA12CA1CA2
SCHEMBL11400330 0.85 MAPT (0.47) GAAMAPTNPSR1CA12CA1
SCHEMBL13601374 0.82 MAPK1 (0.48) GAAMAPTPSIP1MEN1KMT2A
SCHEMBL11561407 0.82 GAA (0.57) GAAMAPTPSIP1CA12CA1
SCHEMBL8951864 0.81 MAPT (0.45) GAAMAPTNPSR1CA12CA1
SCHEMBL11324354 0.81 CA2 (0.50) GAAMAPTNPSR1CA12CA1
SCHEMBL9404072 0.80 CA2 (0.55) GAAMAPTNPSR1CA12CA1
SCHEMBL1370002 0.80 LMNA (0.55) MAPTNPSR1CA12CA1CA2
SCHEMBL3077407 0.79 MAPT (0.57) GAAMAPTNPSR1CA12CA1
SCHEMBL30932826 0.79 MAPT (0.57) GAAMAPTNPSR1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0125356-A1 Filter arrangement for cathode ray tubes Lin, Chii-Hsiung (TW) 1984-11-21 EP claimed
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
EP-0026414-B1 WATER SOLUBLE MONOAZO COMPOUNDS, THEIR PREPARATION AND THEIR USE AS DYESTUFFS IN DYEING AND PRINTING TEXTILE MATERIALS, AS WELL AS THE AMINES PER SE CIBA-GEIGY AG (CH) 1985-04-10 EP disclosed
US-4467088-A USEFULL IN PREPARATION OF DYES CIBA-GEIGY CORPORATION (US) 1984-08-21 US disclosed
EP-0026414-A2 Water soluble monoazo compounds, their preparation and their use as dyestuffs in dyeing and printing textile materials, as well as the amines per se CIBA-GEIGY AG (CH) 1981-04-08 EP disclosed
EP-0010249-A2 Herbicidal agents, process for their preparation and their use in combating weeds BAYER AG (DE) 1980-04-30 EP disclosed
EP-0010250-A2 Use of Sulfonanilides in inhibition of plant growth BAYER AG (DE) 1980-04-30 EP disclosed